Prof Sir Rory Collins had with Fiona Godlee over the publication of the Aseem Malhotra paper where Rory Collins demanded an apology and a retraction of the paper.
They also point out that the said data must be requested from the individual research organisation which carries out the trials, and is not in their gift to provide.
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The error did not compromise the principal arguments being made in either of the articles.
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The conclusions of the BMJ report, which are carefully written are worth considering.
These arguments involve interpretations of available evidence and were deemed to be within the range of reasonable opinion among those who are debating the appropriate use of statins.
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Specific and concrete examples would be required before I could provide any meaningful answer.
To an extent I am cursing myself for doing what I am about to do.
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The panel strongly believes that the current debates on the appropriate use of statins would be elevated and usefully informed by making available the individual patient level data that underpin the relevant studies.
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You often quote observational studies as proof of your claims about statins and cholesterol in articles and in media appearances which contradict findings of authoritative clinical trials, which you do not mention.
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Collins attacks were severe, and the BMJ was require to hold an investigation, in which Collins attacks on these papers were judged to be unfounded.
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Vinay Prasad in Annals of Internal Medicine illustrates a fundamental problem that has consistently concerned the panel.
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This, I trust, gives you some idea of the high level of fact checking going on at the Daily Mail.
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Indeed, I thought long and hard about responding to the allegation that there is no evidence you work in NHS practice, or as a GP in private practice.
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This would have been a complete lie, so I wondered about letting them print it, then suing their backsides off afterwards.
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Feel free to check with either trust, or look me up on the GMC website.
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Unfortunately, patients and clinicians have to make decisions in the grey area between these two diametrically opposed conclusions.
Using a national sample of Veterans Affairs patients with ASCVD (atherosclerotic cardiovascular disease), we found that a low adherence to statin therapy was associated with a greater risk of dying.
Clearly, not enough people have read my book, and I would therefore heartily encourage another million or so people to do so.
Look, I wrote the book Doctoring Data so that you could read papers like this and work out why they are complete nonsense for yourselves'.
He attacked the BMJ for publishing an article suggesting statins may have a high incidence of adverse effects.
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In terms of death and disability that could have been prevented, this could be far worse.
Your stance on statins and the link between cholesterol and heart disease amounts to misinformation.
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It was published in the New England Journal of Medicine (NEJM) a couple of days ago.
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However, the CTT have stated numerous times that they did not originally request the data on all adverse events so did not have it.
Whilst observational studies are not generally considered as robust as randomised clinical trials, they have value.
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In other words, the attacks on Aseem Malhotra were completely unfounded, as were the attacks on the BMJ.
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The panel was unanimous in its decision that the two articles do not meet any of the criteria for retraction.
Which was the most read paper in the journal for five months in a row.
Equally, most epidemiologists would agree that, whilst observational studies (demonstrating association) cannot prove causality (unless the hazard ratios are very high) a lack of association does disprove causation.
But I was quite pleased that they included some of the stuff that I sent.
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In making this assessment, the panel is not expressing an opinion about the merits of these arguments, as that work was beyond the scope of the panel.
They claim do not hold the data, yet they have managed to publish major papers on statin adverse effects?
Yes, I believe that people are being conned, and I believe the public are being deliberately misled.
Doctoring Data, which I would recommend you read, as it outlines the ways that data are presented to look as beneficial as possible.
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It is a version of similar claims you have made numerous times over the years.
But if anyone states that I am not employed in the NHS then I will most certainly sue.
So, it can be fully valid to rely on observational studies where there is no association, or the observation is in direct contradiction to the hypothesis.
LLT, which was funded by the National Institutes of Health in the US.
There is no evidence you work in NHS practice, or as a GP in private practice.
Do I not mention that the studies I quote are observational, or that I do not mention the findings of authoritative clinical trials?
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My advice therefore would be to stop the statins and have nice cup of tea instead.
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In the end I did write back to the Daily Mail, and this is what I said.
In fact, a particularly germane example occurred recently in which two experienced Cochrane groups were charged with evaluating a particular intervention and, despite being given the same instructions, data, and resources, did not arrive at identical results or conclusions.
They say you know this, as they have told you this, so to repeat the claim amounts to a lie.
If you wish for any comments to be included in our article please send them to us by midday this Friday.
The figures quoted by Collins and Baigent and the Oxford CTT group are relative risk reductions, and these figures are entirely meaningless unless you know the absolute risk.
You could perhaps ask them to point you to any letter or any other form of communication that the CTT have had with me.
Women, minorities, younger adults, and older adults were less likely to adhere to statins.
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So, for them to say that they have told me anything is, to be fully accurate, a lie.
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